Kinin B 1 Receptor Acts in Adipose Tissue to Control Fat Distribution in a Cell-Nonautonomous Manner

The kinin B receptor (B R) plays a role in inflammatory and metabolic processes. B R deletion (B ) protects mice from diet-induced obesity and improves insulin and leptin sensitivity. In contrast, genetic reconstitution of B R exclusively in adipose tissue reverses the lean phenotype of B mice. To s...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2019-08, Vol.68 (8), p.1614
Hauptverfasser:	Sales, Vicencia M, Gonçalves-Zillo, Thais, Castoldi, Angela, Burgos, Marina, Branquinho, Jessica, Batista, Carolina, Oliveira, Valeria, Silva, Elton, Castro, Charlles H M, Câmara, Niels, Mori, Marcelo A, Pesquero, João Bosco
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, White - metabolism Adipose Tissue, White - transplantation Animals Body Composition - genetics Body Composition - physiology Diet, High-Fat - adverse effects Flow Cytometry Glucose - metabolism Insulin Resistance - genetics Insulin Resistance - physiology Liver - metabolism Male Mice Receptor, Bradykinin B1 - genetics Receptor, Bradykinin B1 - metabolism Weight Gain - genetics Weight Gain - physiology
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