SALL4-mediated upregulation of exosomal miR-146a-5p drives T-cell exhaustion by M2 tumor-associated macrophages in HCC

Emerging evidence indicates that cancer cell-derived exosomes contribute to cancer progression through the modulation of tumor microenvironment, but the underlying mechanisms are not fully elucidated. Here, we reported that hepatocellular carcinoma (HCC)-derived exosomes could remodel macrophages by...

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Veröffentlicht in:	Oncoimmunology 2019-07, Vol.8 (7), p.1601479-1601479
Hauptverfasser:	Yin, Chunlai, Han, Qiuju, Xu, Dongqing, Zheng, Bingqing, Zhao, Xuemei, Zhang, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Exosome M2 macrophage microenvironment miR-146a-5p Original Research SALL4
Online-Zugang:	Volltext
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