Isolation and Biological Activity of 8-Epitetrodotoxin and the Structure of a Possible Biosynthetic Shunt Product of Tetrodotoxin, Cep-226A, from the Newt Cynops ensicauda popei

Tetrodotoxin (TTX, 1), a potent neurotoxin, has been found in various animal species in both marine and terrestrial environments. In this study, a new TTX analogue, 8-epiTTX (2), and a possible biosynthetic shunt compound of TTX, Cep-226A (3), were isolated from the newt Cynops ensicauda popei. The...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2019-06, Vol.82 (6), p.1656-1663
Hauptverfasser:	Kudo, Yuta, Yotsu-Yamashita, Mari
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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