The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients

To determine the characteristics of trauma patients with low levels of fibrinolysis as detected by viscoelastic hemostatic assay (VHA) and explore the underlying mechanisms of this subtype. Hyperfibrinolysis is a central component of acute traumatic coagulopathy but a group of patients present with...

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Veröffentlicht in:	Annals of surgery 2019-06, Vol.269 (6), p.1184
Hauptverfasser:	Gall, Lewis S, Vulliamy, Paul, Gillespie, Scarlett, Jones, Timothy F, Pierre, Rochelle S J, Breukers, Sabine E, Gaarder, Christine, Juffermans, Nicole P, Maegele, Marc, Stensballe, Jakob, Johansson, Pär I, Davenport, Ross A, Brohi, Karim
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Annexin A2 - blood Blood Coagulation Factors - metabolism Female Fibrin Fibrinogen Degradation Products - metabolism Fibrinolysis - physiology Humans Male Middle Aged Prospective Studies S100 Proteins - blood Survival Rate Thrombelastography Wounds and Injuries - blood Wounds and Injuries - complications Wounds and Injuries - mortality Young Adult
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