Melatonin MT 1 receptor as a novel target in neuropsychopharmacology: MT 1 ligands, pathophysiological and therapeutic implications, and perspectives

Melatonin (MLT), a neuromodulator mainly acting through two G-protein coupled receptors MT and MT , regulates many brain functions, including circadian rhythms, mood, pain and sleep. MLT and non-selective MT /MT receptor agonists are clinically used in neuropsychiatric and/or sleep disorders. Howeve...

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