Increased frequency and FOXP3 expression of human CD8 + CD25 High+ T lymphocytes and its relation to CD4 regulatory T cells in patients with hepatocellular carcinoma

The mechanism of action of CD8 CD25 FOXP3 T cells in hepatocellular carcinoma (HCC) has not been fully understood. Herein, the role of CD8 CD25 FOXP3 T cells in HCC was compared with that of CD4 CD25 FOXP3 regulatory T cells (conventional Tregs). Thirty-five patients with HCC and twenty age and sex-...

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Veröffentlicht in:	Human immunology 2019-07, Vol.80 (7), p.510
Hauptverfasser:	Zahran, Asmaa M, Nafady-Hego, Hanaa, Mansor, Shima G, Abbas, Wael A, Abdel-Malek, Mohamed O, Mekky, Mohamed A, Hetta, Helal F
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over alpha-Fetoproteins - metabolism Biomarkers, Tumor - metabolism Carcinoma, Hepatocellular - blood Carcinoma, Hepatocellular - immunology Case-Control Studies CD8-Positive T-Lymphocytes - metabolism Female Forkhead Transcription Factors - metabolism Humans Interleukin-2 Receptor alpha Subunit - metabolism Liver Neoplasms - blood Liver Neoplasms - immunology Lymphocyte Count Male Middle Aged Prospective Studies T-Lymphocytes, Regulatory - metabolism
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