Amblyomma sculptum Salivary PGE 2 Modulates the Dendritic Cell- Rickettsia rickettsii Interactions in vitro and in vivo

is an important vector of , causative agent of Rocky Mountain spotted fever and the most lethal tick-borne pathogen affecting humans. To feed on the vertebrate host's blood, secretes a salivary mixture, which may interact with skin resident dendritic cells (DCs) and modulate their function. The...

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Veröffentlicht in:	Frontiers in immunology 2019, Vol.10, p.118
Hauptverfasser:	Esteves, Eliane, Bizzarro, Bruna, Costa, Francisco Borges, Ramírez-Hernández, Alejandro, Peti, Ana Paula Ferranti, Cataneo, Allan Henrique Depieri, Wowk, Pryscilla Fanini, Timóteo, Rodolfo Pessato, Labruna, Marcelo Bahia, Silva Junior, Pedro Ismael, Silva, Célio Lopes, Faccioli, Lúcia Helena, Fogaça, Andréa Cristina, Sorgi, Carlos Arterio, Sá-Nunes, Anderson
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Cells, Cultured Cytokines - metabolism Dendritic Cells - drug effects Dendritic Cells - physiology Dinoprostone - metabolism Disease Vectors Female Host Microbial Interactions - physiology Host-Pathogen Interactions - physiology Humans Immunity, Humoral - physiology Inflammation - metabolism Ixodidae - microbiology Lipopolysaccharides - pharmacology Mice Mice, Inbred C3H Rickettsia rickettsii - pathogenicity Rocky Mountain Spotted Fever - microbiology Saliva - metabolism
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