CD56 dim CD16 - Natural Killer Cell Profiling in Melanoma Patients Receiving a Cancer Vaccine and Interferon-α

Natural killer (NK) cells are innate cytotoxic and immunoregulatory lymphocytes that have a central role in anti-tumor immunity and play a critical role in mediating cellular immunity in advanced cancer immunotherapies, such as dendritic cell (DC) vaccines. Our group recently tested a novel recombin...

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Veröffentlicht in:	Frontiers in immunology 2019, Vol.10, p.14
Hauptverfasser:	Vujanovic, Lazar, Chuckran, Christopher, Lin, Yan, Ding, Fei, Sander, Cindy A, Santos, Patricia M, Lohr, Joel, Mashadi-Hossein, Afshin, Warren, Sarah, White, Andy, Huang, Alan, Kirkwood, John M, Butterfield, Lisa H
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen Presentation - immunology Antigen-Presenting Cells - immunology Antigen-Presenting Cells - metabolism Biomarkers Cancer Vaccines - administration & dosage Cancer Vaccines - immunology CD56 Antigen - metabolism Clinical Trials, Phase I as Topic Combined Modality Therapy Cytotoxicity, Immunologic Humans Immunophenotyping Immunotherapy Interferon-alpha - pharmacology Interferon-alpha - therapeutic use Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Lymphocyte Activation - immunology Melanoma - diagnosis Melanoma - immunology Melanoma - metabolism Melanoma - therapy Neoplasm Staging Receptors, IgG - metabolism Treatment Outcome Tumor Microenvironment - immunology
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