Transition metal-free direct dehydrogenative arylation of activated C(sp)-H bonds: synthetic ambit and DFT reactivity predictions

A transition metal-free dehydrogenative method for the direct mono-arylation of a wide range of activated C(sp 3 )-H bonds has been developed. This operationally simple and environmentally friendly aerobic arylation uses tert -BuOK as the base and nitroarenes as electrophiles to prepare up to gram q...

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Veröffentlicht in:	Chemical science (Cambridge) 2018-11, Vol.9 (41), p.7992-7999
Hauptverfasser:	Lovato, Kaitlyn, Guo, Lirong, Xu, Qing-Long, Liu, Fengting, Yousufuddin, Muhammed, Ess, Daniel H, Kürti, László, Gao, Hongyin
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Bonding Crystallography Dehydrogenation Esters Hydrogen bonds Nitriles Prediction models Substrates Sulfones Transition metals X ray spectra
Online-Zugang:	Volltext
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