JAK2V617F, CALR, and MPL Mutations and Bone Marrow Histology in Patients with Essential Thrombocythaemia

Introduction: Mutations in the JAK2, CALR, and MPL genes have been shown to have prognostic value in essential thrombocythaemia (ET), but no clear association with morphological changes has been reported so far. We investigated the possible correlation between gene mutations and histopathological fe...

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Veröffentlicht in:	Acta haematologica 2018, Vol.140 (4), p.234-239
Hauptverfasser:	Pich, Achille, Riera, Ludovica, Francia di Celle, Paola, Beggiato, Eloise, Benevolo, Giulia, Godio, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Bone Marrow - pathology Brief Communication Calreticulin - genetics DNA Mutational Analysis Female Humans Janus Kinase 2 - genetics Male Middle Aged Mutation Receptors, Thrombopoietin - genetics Thrombocythemia, Essential - diagnosis Thrombocythemia, Essential - genetics
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