Scaffold mediated gene knockdown for neuronal differentiation of human neural progenitor cells

The use of human induced pluripotent stem cell-derived neural progenitor cells (hiPSC-NPCs) is an attractive therapeutic option for damaged nerve tissues. To direct neuronal differentiation of stem cells, we have previously developed an electrospun polycaprolactone nanofiber scaffold that was functi...

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Veröffentlicht in:	Biomaterials science 2018-11, Vol.6 (11), p.319-329
Hauptverfasser:	Chooi, Wai Hon, Ong, William, Murray, Aoife, Lin, Junquan, Nizetic, Dean, Chew, Sing Yian
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Adhesion - genetics Cell Differentiation - genetics Cell Movement - genetics Cell Survival - genetics Cells (biology) Differentiation Gene Knockdown Techniques - methods Humans Induced Pluripotent Stem Cells - cytology Migration Nanofibers Neural Stem Cells - cytology Neurites - metabolism Neurons - cytology Polycaprolactone Reagents Ribonucleic acid RNA Scaffolds Spinal cord Stem cells Toxicity
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