MRI tracking of polyethylene glycol-coated superparamagnetic iron oxide-labelled placenta-derived mesenchymal stem cells toward glioblastoma stem-like cells in a mouse model

Mesenchymal stem cells (MSCs) that display homing and infiltration properties towards tumor cells are a promising cellular targeting vector for brain tumor therapy but are limited to local-regional delivery in current preclinical models. Here, we investigated whether placenta-derived MSCs (P-MSCs) a...

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Veröffentlicht in:	Artificial cells, nanomedicine, and biotechnology nanomedicine, and biotechnology, 2018-01, Vol.46 (S3), p.448-459
Hauptverfasser:	Hsu, Fei-Ting, Wei, Zung-Hang, Hsuan, Yogi Chang-Yo, Lin, Willie, Su, Yu-Chin, Liao, Chia-Hui, Hsieh, Chia-Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Blood-brain barrier Bone marrow Brain tumors Cell proliferation cellular MRI Chemokines Cytotoxicity Glioblastoma Glioblastoma stem-like cells Homing Hypoxia Infiltration Iron oxides Labeling Magnetic resonance imaging Medical imaging mesenchymal stem cell tumor-homing Mesenchymal stem cells Mesenchyme Metastases Neuroimaging NMR Nuclear magnetic resonance Placenta placenta-derived mesenchymal stem cells Polyethylene glycol polyethylene glycol-coated superparamagnetic iron oxide Real time Stem cell transplantation Stem cells Therapy Tracking Tropism Tumor cells Tumors
Online-Zugang:	Volltext
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