A Membrane-Targeted Peptide Inhibiting PtxA of Phosphotransferase System Blocks Streptococcus mutans

Streptococcus mutans, the primary cause of dental caries, takes up carbohydrates through the phosphoenolpyruvate sugar phosphotransferase system (PTS). This study aimed to identify a novel membrane-targeted antimicrobial peptide (AMP) that could also target the L-ascorbate-specific PtxA component of...

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Veröffentlicht in:	Caries research 2019-02, Vol.53 (2), p.176-193
Hauptverfasser:	Xiang, Shao-Wen, Shao, Jun, He, Jian, Wu, Xin-Yu, Xu, Xiao-Hu, Zhao, Wang-Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial peptides Biofilms Care and treatment Causes of Control Dental caries Dental Caries - microbiology Dental Caries - prevention & control Dentistry Health aspects Humans Original Paper Peptides Phosphoenolpyruvate Sugar Phosphotransferase System Phosphotransferases Streptococcus mutans Streptococcus mutans - enzymology Testing
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