Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits
Undoped and Fe-doped ZnO nanoparticles (NPs) were synthesized using Amaranthus spinosus leaf extract as a reducing agent. The physicochemical traits, dissolution, cytotoxicity, as well as the antioxidant, photocatalytic and antibacterial activities of synthesized NPs were investigated. The results r...
Gespeichert in:
| Veröffentlicht in: | Toxicology research (Cambridge) 2017-11, Vol.6 (6), p.854-865 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 865 |
|---|---|
| container_issue | 6 |
| container_start_page | 854 |
| container_title | Toxicology research (Cambridge) |
| container_volume | 6 |
| creator | Aiswarya Devi, S Harshiny, M Udaykumar, S Gopinath, P Matheswaran, M |
| description | Undoped and Fe-doped ZnO nanoparticles (NPs) were synthesized using
Amaranthus spinosus
leaf extract as a reducing agent. The physicochemical traits, dissolution, cytotoxicity, as well as the antioxidant, photocatalytic and antibacterial activities of synthesized NPs were investigated. The results revealed that ZnO NPs were rod shaped with hexagonal phase structure, and their crystal size, dissolubility and aggregation decreased with Fe doping of NPs. Cytotoxicity of the NPs was studied against MCF-7 cells by MTT assay. IC
50
values for undoped and 1 wt% Fe-doped ZnO NPs were found to be 400 and 600 μg mL
−1
, respectively. Cell viability with Fe-doped ZnO NPs was higher than with undoped ZnO. Among the synthesized NPs,
A. spinosus
-mediated 1 wt% Fe-doped ZnO shows a better decolourization efficiency of 97% for indigo carmine dye under solar irradiance. The antibacterial activity of NPs was tested against Gram-negative
Escherichia coli
and Gram-positive
Bacillus safensis
using disc diffusion, minimum inhibitory concentration and growth curve method. The bactericidal activity of Fe-doped ZnO NPs was more prominent with
E. coli
than
B. safensis
bacteria and when compared to undoped ZnO.
A relative study on the toxicity, antibacterial activity and physico-chemical traits of pure ZnO and Fe-doped ZnO nanoparticles. |
| doi_str_mv | 10.1039/c7tx00093f |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_30090548</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2086262460</sourcerecordid><originalsourceid>FETCH-LOGICAL-c495t-940ffc967e7787be60d5b7c645a0e8f4f356036f4d31cc0cc92c7940990da2763</originalsourceid><addsrcrecordid>eNp9ks2LFDEQxYMo7jLuxbsS8SJia3WSTro9CDK4KizswRUWLyGdjzFLT9Imadn578066_hx8JRA_d6rV1Qh9LCFly3Q4ZUW5RoABuruoGMCrGtYR_u7hz-5PEInOV9VBgQQTrv76IhWAXSsP0bLp5JUsZsdjg5vbVET9ikGbOLswwarYPAmWRuarTW-ggZ_Cec4qBBnlYrXk82vsfE5x2kZ_eTL7kUVFT8qXWzy1e7GQu9KLPHaa1y7-ZIfoHtOTdme3L4r9Pn03cX6Q3N2_v7j-u1Zo9nQlWZg4JweuLBC9GK0HEw3Cs1Zp8D2jjnacaDcMUNbrUHrgWhRRcMARhHB6Qq92fvOy1gH0DbU_pOck9-qtJNRefl3JfivchO_Sw6c0I5Wg2e3Bil-W2wucuuzttOkgo1LlgR6TjhhNcYKPf0HvYpLCnW8SrXQk7ZlbaWe7ymdYs7JukOYFuTNQuVaXFz-XOhphR__Gf-A_lpfBZ7sgZT1ofr7IuRsXGUe_Y-hPwAmILLc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2010821141</pqid></control><display><type>article</type><title>Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>Royal Society Of Chemistry Journals 2008-</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Aiswarya Devi, S ; Harshiny, M ; Udaykumar, S ; Gopinath, P ; Matheswaran, M</creator><creatorcontrib>Aiswarya Devi, S ; Harshiny, M ; Udaykumar, S ; Gopinath, P ; Matheswaran, M</creatorcontrib><description>Undoped and Fe-doped ZnO nanoparticles (NPs) were synthesized using
Amaranthus spinosus
leaf extract as a reducing agent. The physicochemical traits, dissolution, cytotoxicity, as well as the antioxidant, photocatalytic and antibacterial activities of synthesized NPs were investigated. The results revealed that ZnO NPs were rod shaped with hexagonal phase structure, and their crystal size, dissolubility and aggregation decreased with Fe doping of NPs. Cytotoxicity of the NPs was studied against MCF-7 cells by MTT assay. IC
50
values for undoped and 1 wt% Fe-doped ZnO NPs were found to be 400 and 600 μg mL
−1
, respectively. Cell viability with Fe-doped ZnO NPs was higher than with undoped ZnO. Among the synthesized NPs,
A. spinosus
-mediated 1 wt% Fe-doped ZnO shows a better decolourization efficiency of 97% for indigo carmine dye under solar irradiance. The antibacterial activity of NPs was tested against Gram-negative
Escherichia coli
and Gram-positive
Bacillus safensis
using disc diffusion, minimum inhibitory concentration and growth curve method. The bactericidal activity of Fe-doped ZnO NPs was more prominent with
E. coli
than
B. safensis
bacteria and when compared to undoped ZnO.
A relative study on the toxicity, antibacterial activity and physico-chemical traits of pure ZnO and Fe-doped ZnO nanoparticles.</description><identifier>ISSN: 2045-452X</identifier><identifier>EISSN: 2045-4538</identifier><identifier>DOI: 10.1039/c7tx00093f</identifier><identifier>PMID: 30090548</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Antibacterial activity ; Antioxidants ; Bactericidal activity ; Chemistry ; Color removal ; Crystal structure ; Cytotoxicity ; Decoloring ; Decolorization ; Doping ; E coli ; Hexagonal phase ; Indigo ; Iron ; Irradiance ; Minimum inhibitory concentration ; Nanoparticles ; Solid phases ; Synthesis ; Toxicity ; Zinc oxide</subject><ispartof>Toxicology research (Cambridge), 2017-11, Vol.6 (6), p.854-865</ispartof><rights>Copyright Royal Society of Chemistry 2017</rights><rights>This journal is © The Royal Society of Chemistry 2017 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c495t-940ffc967e7787be60d5b7c645a0e8f4f356036f4d31cc0cc92c7940990da2763</citedby><cites>FETCH-LOGICAL-c495t-940ffc967e7787be60d5b7c645a0e8f4f356036f4d31cc0cc92c7940990da2763</cites><orcidid>0000-0003-4158-1705</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062353/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062353/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30090548$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aiswarya Devi, S</creatorcontrib><creatorcontrib>Harshiny, M</creatorcontrib><creatorcontrib>Udaykumar, S</creatorcontrib><creatorcontrib>Gopinath, P</creatorcontrib><creatorcontrib>Matheswaran, M</creatorcontrib><title>Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits</title><title>Toxicology research (Cambridge)</title><addtitle>Toxicol Res (Camb)</addtitle><description>Undoped and Fe-doped ZnO nanoparticles (NPs) were synthesized using
Amaranthus spinosus
leaf extract as a reducing agent. The physicochemical traits, dissolution, cytotoxicity, as well as the antioxidant, photocatalytic and antibacterial activities of synthesized NPs were investigated. The results revealed that ZnO NPs were rod shaped with hexagonal phase structure, and their crystal size, dissolubility and aggregation decreased with Fe doping of NPs. Cytotoxicity of the NPs was studied against MCF-7 cells by MTT assay. IC
50
values for undoped and 1 wt% Fe-doped ZnO NPs were found to be 400 and 600 μg mL
−1
, respectively. Cell viability with Fe-doped ZnO NPs was higher than with undoped ZnO. Among the synthesized NPs,
A. spinosus
-mediated 1 wt% Fe-doped ZnO shows a better decolourization efficiency of 97% for indigo carmine dye under solar irradiance. The antibacterial activity of NPs was tested against Gram-negative
Escherichia coli
and Gram-positive
Bacillus safensis
using disc diffusion, minimum inhibitory concentration and growth curve method. The bactericidal activity of Fe-doped ZnO NPs was more prominent with
E. coli
than
B. safensis
bacteria and when compared to undoped ZnO.
A relative study on the toxicity, antibacterial activity and physico-chemical traits of pure ZnO and Fe-doped ZnO nanoparticles.</description><subject>Antibacterial activity</subject><subject>Antioxidants</subject><subject>Bactericidal activity</subject><subject>Chemistry</subject><subject>Color removal</subject><subject>Crystal structure</subject><subject>Cytotoxicity</subject><subject>Decoloring</subject><subject>Decolorization</subject><subject>Doping</subject><subject>E coli</subject><subject>Hexagonal phase</subject><subject>Indigo</subject><subject>Iron</subject><subject>Irradiance</subject><subject>Minimum inhibitory concentration</subject><subject>Nanoparticles</subject><subject>Solid phases</subject><subject>Synthesis</subject><subject>Toxicity</subject><subject>Zinc oxide</subject><issn>2045-452X</issn><issn>2045-4538</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp9ks2LFDEQxYMo7jLuxbsS8SJia3WSTro9CDK4KizswRUWLyGdjzFLT9Imadn578066_hx8JRA_d6rV1Qh9LCFly3Q4ZUW5RoABuruoGMCrGtYR_u7hz-5PEInOV9VBgQQTrv76IhWAXSsP0bLp5JUsZsdjg5vbVET9ikGbOLswwarYPAmWRuarTW-ggZ_Cec4qBBnlYrXk82vsfE5x2kZ_eTL7kUVFT8qXWzy1e7GQu9KLPHaa1y7-ZIfoHtOTdme3L4r9Pn03cX6Q3N2_v7j-u1Zo9nQlWZg4JweuLBC9GK0HEw3Cs1Zp8D2jjnacaDcMUNbrUHrgWhRRcMARhHB6Qq92fvOy1gH0DbU_pOck9-qtJNRefl3JfivchO_Sw6c0I5Wg2e3Bil-W2wucuuzttOkgo1LlgR6TjhhNcYKPf0HvYpLCnW8SrXQk7ZlbaWe7ymdYs7JukOYFuTNQuVaXFz-XOhphR__Gf-A_lpfBZ7sgZT1ofr7IuRsXGUe_Y-hPwAmILLc</recordid><startdate>20171101</startdate><enddate>20171101</enddate><creator>Aiswarya Devi, S</creator><creator>Harshiny, M</creator><creator>Udaykumar, S</creator><creator>Gopinath, P</creator><creator>Matheswaran, M</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-4158-1705</orcidid></search><sort><creationdate>20171101</creationdate><title>Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits</title><author>Aiswarya Devi, S ; Harshiny, M ; Udaykumar, S ; Gopinath, P ; Matheswaran, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495t-940ffc967e7787be60d5b7c645a0e8f4f356036f4d31cc0cc92c7940990da2763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Antibacterial activity</topic><topic>Antioxidants</topic><topic>Bactericidal activity</topic><topic>Chemistry</topic><topic>Color removal</topic><topic>Crystal structure</topic><topic>Cytotoxicity</topic><topic>Decoloring</topic><topic>Decolorization</topic><topic>Doping</topic><topic>E coli</topic><topic>Hexagonal phase</topic><topic>Indigo</topic><topic>Iron</topic><topic>Irradiance</topic><topic>Minimum inhibitory concentration</topic><topic>Nanoparticles</topic><topic>Solid phases</topic><topic>Synthesis</topic><topic>Toxicity</topic><topic>Zinc oxide</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aiswarya Devi, S</creatorcontrib><creatorcontrib>Harshiny, M</creatorcontrib><creatorcontrib>Udaykumar, S</creatorcontrib><creatorcontrib>Gopinath, P</creatorcontrib><creatorcontrib>Matheswaran, M</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Toxicology research (Cambridge)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aiswarya Devi, S</au><au>Harshiny, M</au><au>Udaykumar, S</au><au>Gopinath, P</au><au>Matheswaran, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits</atitle><jtitle>Toxicology research (Cambridge)</jtitle><addtitle>Toxicol Res (Camb)</addtitle><date>2017-11-01</date><risdate>2017</risdate><volume>6</volume><issue>6</issue><spage>854</spage><epage>865</epage><pages>854-865</pages><issn>2045-452X</issn><eissn>2045-4538</eissn><abstract>Undoped and Fe-doped ZnO nanoparticles (NPs) were synthesized using
Amaranthus spinosus
leaf extract as a reducing agent. The physicochemical traits, dissolution, cytotoxicity, as well as the antioxidant, photocatalytic and antibacterial activities of synthesized NPs were investigated. The results revealed that ZnO NPs were rod shaped with hexagonal phase structure, and their crystal size, dissolubility and aggregation decreased with Fe doping of NPs. Cytotoxicity of the NPs was studied against MCF-7 cells by MTT assay. IC
50
values for undoped and 1 wt% Fe-doped ZnO NPs were found to be 400 and 600 μg mL
−1
, respectively. Cell viability with Fe-doped ZnO NPs was higher than with undoped ZnO. Among the synthesized NPs,
A. spinosus
-mediated 1 wt% Fe-doped ZnO shows a better decolourization efficiency of 97% for indigo carmine dye under solar irradiance. The antibacterial activity of NPs was tested against Gram-negative
Escherichia coli
and Gram-positive
Bacillus safensis
using disc diffusion, minimum inhibitory concentration and growth curve method. The bactericidal activity of Fe-doped ZnO NPs was more prominent with
E. coli
than
B. safensis
bacteria and when compared to undoped ZnO.
A relative study on the toxicity, antibacterial activity and physico-chemical traits of pure ZnO and Fe-doped ZnO nanoparticles.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>30090548</pmid><doi>10.1039/c7tx00093f</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-4158-1705</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2045-452X |
| ispartof | Toxicology research (Cambridge), 2017-11, Vol.6 (6), p.854-865 |
| issn | 2045-452X 2045-4538 |
| language | eng |
| recordid | cdi_pubmed_primary_30090548 |
| source | Oxford University Press Journals All Titles (1996-Current); Royal Society Of Chemistry Journals 2008-; PubMed Central; Alma/SFX Local Collection |
| subjects | Antibacterial activity Antioxidants Bactericidal activity Chemistry Color removal Crystal structure Cytotoxicity Decoloring Decolorization Doping E coli Hexagonal phase Indigo Iron Irradiance Minimum inhibitory concentration Nanoparticles Solid phases Synthesis Toxicity Zinc oxide |
| title | Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T00%3A09%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Strategy%20of%20metal%20iron%20doping%20and%20green-mediated%20ZnO%20nanoparticles:%20dissolubility,%20antibacterial%20and%20cytotoxic%20traits&rft.jtitle=Toxicology%20research%20(Cambridge)&rft.au=Aiswarya%20Devi,%20S&rft.date=2017-11-01&rft.volume=6&rft.issue=6&rft.spage=854&rft.epage=865&rft.pages=854-865&rft.issn=2045-452X&rft.eissn=2045-4538&rft_id=info:doi/10.1039/c7tx00093f&rft_dat=%3Cproquest_pubme%3E2086262460%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2010821141&rft_id=info:pmid/30090548&rfr_iscdi=true |