Structural basis for the substrate recognition of peptidoglycan pentapeptides by Enterococcus faecalis VanY B

Vancomycin resistance in Enterococci and its transfer to methicillin-resistant Staphylococcus aureus are challenging problems in health care institutions worldwide. High-level vancomycin resistance is conferred by acquiring either transposable elements of the VanA or VanB type. Enterococcus faecalis...

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Veröffentlicht in:	International journal of biological macromolecules 2018-11, Vol.119, p.335
Hauptverfasser:	Kim, Hyoun Sook, Hahn, Hyunggu, Kim, Jieun, Jang, Dong Man, Lee, Ji Yeon, Back, Jang Mi, Im, Ha Na, Kim, Haelee, Han, Byung Woo, Suh, Se Won
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Catalytic Domain Enterococcus faecalis - chemistry Enterococcus faecalis - enzymology Ligands Models, Molecular Molecular Structure Oligopeptides - chemistry Peptide Hydrolases - chemistry Peptide Hydrolases - metabolism Peptidoglycan - chemistry Protein Binding Protein Conformation Substrate Specificity Zinc - chemistry
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