Backbone 1 H, 13 C, and 15 N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

The glucocorticoid receptor (GR) is a nuclear hormone receptor that regulates key genes controlling development, metabolism, and the immune response. GR agonists are efficacious for treatment of inflammatory, allergic, and immunological disorders. Steroid hormone binding to the ligand-binding domain...

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Veröffentlicht in:	Biomolecular NMR assignments 2018-10, Vol.12 (2), p.263
Hauptverfasser:	Köhler, Christian, Carlström, Göran, Tångefjord, Stefan, Papavoine, Tineke, Lepistö, Matti, Edman, Karl, Akke, Mikael
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Ligands Models, Molecular Mutant Proteins - chemistry Mutant Proteins - genetics Mutant Proteins - metabolism Mutation Nuclear Magnetic Resonance, Biomolecular Protein Binding Protein Domains Receptors, Glucocorticoid - chemistry Receptors, Glucocorticoid - genetics Receptors, Glucocorticoid - metabolism
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