The use of chitosan/PLA nano-fibers by emulsion eletrospinning for periodontal tissue engineering

Objective: In this study, nanofibrous scaffolds base on pure polylactic acid (PLA) and chitosan/PLA blends were fabricated by emulsion eletrospinning. By modulating their mechanical and biological properties, cell-compatible and biodegradable scaffolds were developed for periodontal bone regeneratio...

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Veröffentlicht in:	Artificial cells, nanomedicine, and biotechnology nanomedicine, and biotechnology, 2018-01, Vol.46 (sup2), p.419-430
Hauptverfasser:	Shen, Renze, Xu, Weihong, Xue, Yanxiang, Chen, Luyuan, Ye, Haicheng, Zhong, Enyi, Ye, Zhanchao, Gao, Jie, Yan, Yurong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion tests Alizarin Biocompatibility Biodegradability Biological properties Biomedical materials Bone growth Bone marrow Cbfa-1 protein Cell adhesion Cell adhesion & migration Cell proliferation Chitosan Collagen (type I) Differentiation (biology) Extracellular matrix Fiber strength Fibers Gene expression Hydrophobicity Inflammation Interleukin 1 Interleukin 6 Interleukin 8 Mechanical properties Mineralization Morphology Nano-fibers Nanofibers Osteoprotegerin periodontal Periodontal ligament Polylactic acid Polymerase chain reaction Regeneration Regeneration (physiology) Reverse transcription Scaffolds Scanning electron microscopy Stem cells Tissue engineering Toll-like receptor 4 Toll-like receptors Weight
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