Effect of calorie restriction on in vivo glucose metabolism by individual tissues in rats

We evaluated the effects of 8 mo of calorie restriction [CR: 60% of ad libitum (AL) food intake] on glucose uptake by 14 tissues in unanesthetized, adult (12 mo) F344×BN rats. Glucose metabolism was assessed by the 2-[ H]deoxyglucose tracer technique at 1500 or 2100. Despite an ∼60% decline in insul...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 1999-04, Vol.276 (4), p.E728
Hauptverfasser: Wetter, Thomas J, Gazdag, Annie C, Dean, David J, Cartee, Gregory D
Format: Artikel
Sprache:eng
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