Myosin isoform shifts and decreased reactivity in hypoxia-induced hypertensive pulmonary arterial muscle

The principal stimulus that evokes pulmonary hypertension is chronic alveolar hypoxia. Pulmonary hypertension is associated with remodeling of the vessel walls, involving hypertrophy and hyperplasia of pulmonary arterial smooth muscle (PASM) and a concomitant increase in the deposition of connective...

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Veröffentlicht in:American journal of physiology. Lung cellular and molecular physiology 1998-05, Vol.274 (5), p.L775
Hauptverfasser: Packer, C S, Roepke, J E, Oberlies, N H, Rhoades, R A
Format: Artikel
Sprache:eng
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