The novel piperazine-containing compound LQFM018: Necroptosis cell death mechanisms, dopamine D 4 receptor binding and toxicological assessment

Piperazine is a promising scaffold for drug development due to its broad spectrum of biological activities. Based on this, the new piperazine-containing compound LQFM018 (2) [ethyl 4-((1-(4-chlorophenyl)-1H-pyrazol-4-yl)methyl)piperazine-1-carboxylate] was synthetized and some biological activities...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2018-06, Vol.102, p.481
Hauptverfasser:	Costa, Fabiana Bettanin, Cortez, Alane P, de Ávila, Renato Ivan, de Carvalho, Flávio S, Andrade, Wanessa M, da Cruz, Andrezza F, Reis, Karinna B, Menegatti, Ricardo, Lião, Luciano M, Romeiro, Luiz Antônio S, Noël, François, Fraga, Carlos Alberto M, Barreiro, Eliezer J, Sanz, Germán, Rodrigues, Marcella F, Vaz, Boniek G, Valadares, Marize Campos
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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