Microglial activation and amyloid-β clearance induced by exogenous heat-shock proteins

SPECIFIC AIMS We addressed the hypothesis that extracellular heat shock proteins (HSPs) induce microglial activation resulting in cytokine production and clearance of amyloid-β peptide (Aβ). The effects of exogenous HSP90, HSP70, and HSP32 on the production of interleukin 6 (IL-6) and tumor necrosis...

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Veröffentlicht in:	The FASEB journal 2002-04, Vol.16 (6), p.601
Hauptverfasser:	Kakimura, Jun-Ichi, Kitamura, Yoshihisa, Takata, Kazuyuki, Umeki, Masaaki, Suzuki, Sanae, Shibagaki, Keiichi, Taniguchi, Takashi, Nomura, Yasuyuki, Gebicke-Haerter, Peter J, Smith, Mark A, Perry, George, Shimohama, Shun
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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