Attenuated accumulation of Treg cells and reduced production of IL-10 lead to the exacerbation of tissue injury in a mouse model of ARDS

Acute respiratory distress syndrome (ARDS) is a pathological condition that involves diffuse lung injury and severe hypoxemia caused by pulmonary and systemic diseases. We have established a mouse model of severe ARDS, developed by intratracheal injection of α-galactosylceramide (α-GalCer), an activ...

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Veröffentlicht in:Microbiology and immunology 2017-12
Hauptverfasser: Toyama, Masahiko, Kudo, Daisuke, Aoyagi, Tetsuji, Miyasaka, Tomomitsu, Ishii, Keiko, Kanno, Emi, Kaku, Mitsuo, Kushimoto, Shigeki, Kawakami, Kazuyoshi
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Sprache:eng
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