DNA hypermethylation as a predictor of extramural vascular invasion (EMVI) in rectal cancer

Purpose: DNA hypermethylation in gene promoter regions (CpG islands) is emerging as an important pathway in colorectal cancer tumourigenesis. Whilst genetic mutations have been associated with extramural vascular invasion (EMVI) in rectal cancer, no such association has yet been made with epigenetic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer biology & therapy 2018-03, Vol.19 (3), p.214-221
Hauptverfasser:	Kokelaar, Rory F., Jones, Huw G., Williamson, Jeremy, Williams, Namor, Griffiths, A. Paul, Beynon, John, Jenkins, Gareth J., Harris, Dean A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over CIMP CpG Islands - genetics Disease-Free Survival DNA Methylation DNA, Neoplasm - genetics DNA, Neoplasm - isolation & purification Epigenesis, Genetic Epigenetics Female Follow-Up Studies Humans Kaplan-Meier Estimate Male Middle Aged Neoplasm Invasiveness - genetics Neovascularization, Pathologic - genetics Neovascularization, Pathologic - mortality Neovascularization, Pathologic - pathology Neovascularization, Pathologic - surgery Original Prospective Studies Rectal Cancer Rectal Neoplasms - genetics Rectal Neoplasms - mortality Rectal Neoplasms - pathology Rectal Neoplasms - surgery Rectum - pathology Rectum - surgery Vascular Invasion
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!