Stability and recovery of DNA origami structure with cation concentration

Stability and recovery of DNA origami structure with cation concentration

We synthesized triangular and rectangular DNA origami nanostructures and investigated the stability and recovery of them under low cation concentration. Our results demonstrated that the origami nanostructures would melt when incubated in low cation concentration, and recover whilst kept in the conc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nanotechnology 2018-01, Vol.29 (3), p.035102
Hauptverfasser: Chen, Yi, Wang, Ping, Liu, Yang, Liu, Ting, Xu, Yan, Zhu, Shanshan, Zhu, Jun, Ye, Kai, Huang, Guang, Dannong, He
Format: Artikel
Sprache:eng
Schlagworte:
cation concentration
Cations
DNA - chemistry
DNA origami
Fluorescence
Microscopy, Atomic Force
Nucleic Acid Conformation
structural stability
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We synthesized triangular and rectangular DNA origami nanostructures and investigated the stability and recovery of them under low cation concentration. Our results demonstrated that the origami nanostructures would melt when incubated in low cation concentration, and recover whilst kept in the concentration for less than 10 min. However, extending the incubation time would lead to irreversible melting. Our results show the possibility of application of DNA origami nanostructures for things such as a sensor for cation concentration response, etc.
ISSN:0957-4484
1361-6528
DOI:10.1088/1361-6528/aa9dad