The magnitude and duration of direct myocardial depression following intracoronary local anesthetics: a comparison of lidocaine and bupivacaine

Direct myocardial depression plays a role in the cardiovascular toxicity of local anesthetic agents, but this role is obscured by concomitant cardiac, systemic, and CNS events: seizures, hypoxia, acidosis, sympathetic activation, bradycardia, and A-V heart block. Direct injection of small bolus dose...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 1989-02, Vol.70 (2), p.280-287
1. Verfasser:	BUFFINGTON, C. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Local - administration & dosage Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Bupivacaine - administration & dosage Coronary Vessels Depression, Chemical Dogs Halothane - administration & dosage Injections, Intra-Arterial Medical sciences Myocardial Contraction - drug effects Neuropharmacology Pharmacology. Drug treatments Time Factors
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