F 2 -isoprostanes can mediate bleomycin-induced lung fibrosis

F -isoprostanes (F -IsoPs) have been considered markers of oxidative stress in various pulmonary diseases, but little is known about their possible role in pulmonary fibrosis. In this study, we have investigated the potential key role of F -IsoPs as markers and mediators of bleomycin (BLM)-induced p...

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Veröffentlicht in:	Free radical biology & medicine 2018-02, Vol.115, p.1
Hauptverfasser:	Arezzini, Beatrice, Vecchio, Daniela, Signorini, Cinzia, Stringa, Blerta, Gardi, Concetta
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Biomarkers - metabolism Bleomycin - toxicity Cell Differentiation Cell Proliferation Cells, Cultured Collagen - metabolism Disease Models, Animal F2-Isoprostanes - metabolism Fibroblasts - physiology Humans Lung - metabolism Lung - pathology Male Myofibroblasts - physiology Pulmonary Fibrosis - diagnosis Rats Rats, Sprague-Dawley
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