Vecuronium in Alcoholic Liver Disease: A Pharmacokinetic and Pharmacodynamic Analysis

To determine the effect of alcoholic liver disease on the pharmacokinetics and pharmacodynamics of vecuronium, the authors administered vecuronium 0.1 mg ± kg iv to ten surgical patients with alcoholic liver disease and ten healthy surgical patients. All patients were anesthetized with nitrous oxide...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 1988-05, Vol.68 (5), p.771-776
Hauptverfasser:	Arden, James R, Lynam, Daniel P, Castagnoli, Kay P, Canfell, P Claver, Cannon, John C, Miller, Ronald D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthetics. Neuromuscular blocking agents Biological and medical sciences Hepatitis, Alcoholic - complications Hepatitis, Alcoholic - metabolism Humans Liver Cirrhosis, Alcoholic - complications Liver Cirrhosis, Alcoholic - metabolism Liver Diseases, Alcoholic - complications Liver Diseases, Alcoholic - metabolism Medical sciences Middle Aged Neuromuscular Junction - drug effects Neuropharmacology Pharmacology. Drug treatments Surgical Procedures, Operative Vecuronium Bromide - pharmacokinetics Vecuronium Bromide - pharmacology
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