Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein

Polyketides are secondary metabolites which display both valuable pharmaceutical and agrochemical properties. Biosynthesis is performed by polyketide synthases (PKSs), and the acyl carrier protein (ACP), a small acidic protein, that transports the growing polyketide chain and is essential for activi...

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Veröffentlicht in:	Chemical science (Cambridge) 2016-03, Vol.7 (3), p.1779-1785
Hauptverfasser:	Dong, Xu, Bailey, Christopher D, Williams, Christopher, Crosby, John, Simpson, Thomas J, Willis, Christine L, Crump, Matthew P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic compounds Binding Carriers Chains Chemistry Fatty acids Polarity Proteins Transport
Online-Zugang:	Volltext
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