Secretory phospholipase A 2 -IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response

Secretory phospholipase A Group-IIA (sPLA -IIA) is involved in lipid catabolism and growth promoting activity. sPLA -IIA is deregulated in many pathological conditions including various cancers. Here, we have studied the role of sPLA -IIA in the development of cyclic alopecia and wound healing respo...

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Veröffentlicht in:	Scientific reports 2017-09, Vol.7 (1), p.11619
Hauptverfasser:	Chovatiya, Gopal L, Sarate, Rahul M, Sunkara, Raghava R, Gawas, Nilesh P, Kala, Vineet, Waghmare, Sanjeev K
Format:	Artikel
Sprache:	eng
Schlagworte:	Alopecia - etiology Alopecia - metabolism Alopecia - pathology Animals Biomarkers Disease Models, Animal Fluorescent Antibody Technique Gene Expression Regulation Genotype Group II Phospholipases A2 - genetics Group II Phospholipases A2 - metabolism Hair - pathology Hair Follicle - metabolism Hair Follicle - pathology Mice Mice, Transgenic Phenotype Signal Transduction Wound Healing - genetics
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