Homeostatic control of metabolic and functional fitness of T reg cells by LKB1 signalling

Regulatory T cells (T cells) have a pivotal role in the establishment and maintenance of immunological self-tolerance and homeostasis. Transcriptional programming of regulatory mechanisms facilitates the functional activation of T cells in the prevention of diverse types of inflammatory responses. I...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2017-08, Vol.548 (7669), p.602
Hauptverfasser:	Yang, Kai, Blanco, Daniel Bastardo, Neale, Geoffrey, Vogel, Peter, Avila, Julian, Clish, Clary B, Wu, Chuan, Shrestha, Sharad, Rankin, Sherri, Long, Lingyun, Kc, Anil, Chi, Hongbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis beta Catenin - metabolism Cell Survival - genetics Cytokines - metabolism Dendritic Cells - immunology Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Glucocorticoid-Induced TNFR-Related Protein - metabolism Homeostasis Immune Tolerance Mice Mitochondria - metabolism Mitochondria - pathology Programmed Cell Death 1 Receptor - antagonists & inhibitors Programmed Cell Death 1 Receptor - biosynthesis Programmed Cell Death 1 Receptor - metabolism Protein-Serine-Threonine Kinases - deficiency Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Receptors, OX40 - metabolism Receptors, Tumor Necrosis Factor - metabolism Signal Transduction T-Lymphocytes, Regulatory - cytology T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Th2 Cells - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!