Autophagy-monitoring and autophagy-deficient mice

Discovery of yeast autophagy-related (ATG) genes and subsequent identification of their homologs in other organisms have enabled researchers to investigate physiological functions of macroautophagy/autophagy using genetic techniques. Specific identification of autophagy-related structures is importa...

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Veröffentlicht in:	Autophagy 2017-10, Vol.13 (10), p.1619-1628
Hauptverfasser:	Kuma, Akiko, Komatsu, Masaaki, Mizushima, Noboru
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals autophagy Autophagy - genetics Autophagy - physiology Autophagy-Related Proteins - genetics Autophagy-Related Proteins - metabolism Humans knockout mouse Mice Mice, Knockout Mitochondria - physiology Mitochondrial Degradation - genetics Mitochondrial Degradation - physiology mitophagy reporter mouse Review Saccharomyces cerevisiae - genetics selective autophagy Signal Transduction - genetics
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