Topography on a subcellular scale modulates cellular adhesions and actin stress fiber dynamics in tumor associated fibroblasts

Cells can sense and adapt to mechanical properties of their environment. The local geometry of the extracellular matrix, such as its topography, has been shown to modulate cell morphology, migration, and proliferation. Here we investigate the effect of micro/nanotopography on the morphology and cyto...

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Veröffentlicht in:	Physical biology 2017-11, Vol.14 (6), p.065003-065003
Hauptverfasser:	Azatov, Mikheil, Sun, Xiaoyu, Suberi, Alexandra, Fourkas, John T, Upadhyaya, Arpita
Format:	Artikel
Sprache:	eng
Schlagworte:	actin Actins - metabolism Cancer-Associated Fibroblasts - physiology Cell Adhesion cytoskeleton focal adhesion Focal Adhesions - physiology Humans Nanostructures - analysis stress fiber Stress Fibers - metabolism topography
Online-Zugang:	Volltext
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