Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis

Despite decades of research on necrotizing enterocolitis, we still do not fully understand the pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of recent significant advances in the microbiology, molecular biology, and cell biology of the intestine of preterm i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neonatology (Basel, Switzerland) Switzerland), 2017-01, Vol.111 (4), p.423-430
Hauptverfasser: Eaton, Simon, Rees, Clare M., Hall, Nigel J.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 430
container_issue 4
container_start_page 423
container_title Neonatology (Basel, Switzerland)
container_volume 111
creator Eaton, Simon
Rees, Clare M.
Hall, Nigel J.
description Despite decades of research on necrotizing enterocolitis, we still do not fully understand the pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of recent significant advances in the microbiology, molecular biology, and cell biology of the intestine of preterm infants and infants with necrotizing enterocolitis, there is some hope that research into this devastating disease will yield some important translation into effective prevention, more rapid diagnosis, and novel therapies.
doi_str_mv 10.1159/000458462
format Article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmed_primary_28538238</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A637318302</galeid><sourcerecordid>A637318302</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-4d2dfd3287819b45ea7a5369676f9db96a6887821792e036ee48f82e696684263</originalsourceid><addsrcrecordid>eNo90MtLwzAcB_Agio_pwbtITqLgNI82TY9jzAf4QvQcsvbXNtomM0kP86-3Y3OnBPL5PfJF6JSSG0rT_JYQkqQyEWwHHVIh6DiTNN_d3gk5QEchfBGSpqlg--iAyZRLxuUhUtPee7ARv0MA7YsGO4tjA3i2MCV0xrWuXl7jNx0bV4OFYMI11rbEz9rqGrpVqavwCxTeRfNrbI1nNoJ3hWtNNOEY7VW6DXCyOUfo8272MX0YP73eP04nT-OCZyyOk5KVVcmZXG0-T1LQmU65yEUmqryc50ILObwxmuUMCBcAiawkg0EImTDBR-hy3Xfh3U8PIarOhALaVltwfVA0JyyRTHI20Is1rXULqgHdxia4to_G2aAmgmecSk5W8GoNh7-F4KFSC2867ZeKErUKXm2DH-z5Zn4_76Dcyv-kB3C2Bt_a1-C3YFP_B6BIhOQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1902482832</pqid></control><display><type>article</type><title>Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis</title><source>MEDLINE</source><source>Karger Journals</source><source>Alma/SFX Local Collection</source><creator>Eaton, Simon ; Rees, Clare M. ; Hall, Nigel J.</creator><creatorcontrib>Eaton, Simon ; Rees, Clare M. ; Hall, Nigel J.</creatorcontrib><description>Despite decades of research on necrotizing enterocolitis, we still do not fully understand the pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of recent significant advances in the microbiology, molecular biology, and cell biology of the intestine of preterm infants and infants with necrotizing enterocolitis, there is some hope that research into this devastating disease will yield some important translation into effective prevention, more rapid diagnosis, and novel therapies.</description><identifier>ISSN: 1661-7800</identifier><identifier>EISSN: 1661-7819</identifier><identifier>DOI: 10.1159/000458462</identifier><identifier>PMID: 28538238</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Care and treatment ; Development and progression ; Enteral Nutrition ; Enterocolitis, Necrotizing - epidemiology ; Enterocolitis, Necrotizing - physiopathology ; Enterocolitis, Necrotizing - prevention &amp; control ; Enterocolitis, Necrotizing - therapy ; Gastrointestinal Microbiome ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Necrotizing enterocolitis ; Pediatric research ; Randomized Controlled Trials as Topic ; Review ; Risk factors</subject><ispartof>Neonatology (Basel, Switzerland), 2017-01, Vol.111 (4), p.423-430</ispartof><rights>2017 S. Karger AG, Basel</rights><rights>2017 S. Karger AG, Basel.</rights><rights>COPYRIGHT 2017 S. Karger AG</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-4d2dfd3287819b45ea7a5369676f9db96a6887821792e036ee48f82e696684263</citedby><cites>FETCH-LOGICAL-c372t-4d2dfd3287819b45ea7a5369676f9db96a6887821792e036ee48f82e696684263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,2423,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28538238$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eaton, Simon</creatorcontrib><creatorcontrib>Rees, Clare M.</creatorcontrib><creatorcontrib>Hall, Nigel J.</creatorcontrib><title>Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis</title><title>Neonatology (Basel, Switzerland)</title><addtitle>Neonatology</addtitle><description>Despite decades of research on necrotizing enterocolitis, we still do not fully understand the pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of recent significant advances in the microbiology, molecular biology, and cell biology of the intestine of preterm infants and infants with necrotizing enterocolitis, there is some hope that research into this devastating disease will yield some important translation into effective prevention, more rapid diagnosis, and novel therapies.</description><subject>Care and treatment</subject><subject>Development and progression</subject><subject>Enteral Nutrition</subject><subject>Enterocolitis, Necrotizing - epidemiology</subject><subject>Enterocolitis, Necrotizing - physiopathology</subject><subject>Enterocolitis, Necrotizing - prevention &amp; control</subject><subject>Enterocolitis, Necrotizing - therapy</subject><subject>Gastrointestinal Microbiome</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Necrotizing enterocolitis</subject><subject>Pediatric research</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Review</subject><subject>Risk factors</subject><issn>1661-7800</issn><issn>1661-7819</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo90MtLwzAcB_Agio_pwbtITqLgNI82TY9jzAf4QvQcsvbXNtomM0kP86-3Y3OnBPL5PfJF6JSSG0rT_JYQkqQyEWwHHVIh6DiTNN_d3gk5QEchfBGSpqlg--iAyZRLxuUhUtPee7ARv0MA7YsGO4tjA3i2MCV0xrWuXl7jNx0bV4OFYMI11rbEz9rqGrpVqavwCxTeRfNrbI1nNoJ3hWtNNOEY7VW6DXCyOUfo8272MX0YP73eP04nT-OCZyyOk5KVVcmZXG0-T1LQmU65yEUmqryc50ILObwxmuUMCBcAiawkg0EImTDBR-hy3Xfh3U8PIarOhALaVltwfVA0JyyRTHI20Is1rXULqgHdxia4to_G2aAmgmecSk5W8GoNh7-F4KFSC2867ZeKErUKXm2DH-z5Zn4_76Dcyv-kB3C2Bt_a1-C3YFP_B6BIhOQ</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Eaton, Simon</creator><creator>Rees, Clare M.</creator><creator>Hall, Nigel J.</creator><general>S. Karger AG</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170101</creationdate><title>Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis</title><author>Eaton, Simon ; Rees, Clare M. ; Hall, Nigel J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-4d2dfd3287819b45ea7a5369676f9db96a6887821792e036ee48f82e696684263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Care and treatment</topic><topic>Development and progression</topic><topic>Enteral Nutrition</topic><topic>Enterocolitis, Necrotizing - epidemiology</topic><topic>Enterocolitis, Necrotizing - physiopathology</topic><topic>Enterocolitis, Necrotizing - prevention &amp; control</topic><topic>Enterocolitis, Necrotizing - therapy</topic><topic>Gastrointestinal Microbiome</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Necrotizing enterocolitis</topic><topic>Pediatric research</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Review</topic><topic>Risk factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eaton, Simon</creatorcontrib><creatorcontrib>Rees, Clare M.</creatorcontrib><creatorcontrib>Hall, Nigel J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neonatology (Basel, Switzerland)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eaton, Simon</au><au>Rees, Clare M.</au><au>Hall, Nigel J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis</atitle><jtitle>Neonatology (Basel, Switzerland)</jtitle><addtitle>Neonatology</addtitle><date>2017-01-01</date><risdate>2017</risdate><volume>111</volume><issue>4</issue><spage>423</spage><epage>430</epage><pages>423-430</pages><issn>1661-7800</issn><eissn>1661-7819</eissn><abstract>Despite decades of research on necrotizing enterocolitis, we still do not fully understand the pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of recent significant advances in the microbiology, molecular biology, and cell biology of the intestine of preterm infants and infants with necrotizing enterocolitis, there is some hope that research into this devastating disease will yield some important translation into effective prevention, more rapid diagnosis, and novel therapies.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>28538238</pmid><doi>10.1159/000458462</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1661-7800
ispartof Neonatology (Basel, Switzerland), 2017-01, Vol.111 (4), p.423-430
issn 1661-7800
1661-7819
language eng
recordid cdi_pubmed_primary_28538238
source MEDLINE; Karger Journals; Alma/SFX Local Collection
subjects Care and treatment
Development and progression
Enteral Nutrition
Enterocolitis, Necrotizing - epidemiology
Enterocolitis, Necrotizing - physiopathology
Enterocolitis, Necrotizing - prevention & control
Enterocolitis, Necrotizing - therapy
Gastrointestinal Microbiome
Humans
Infant
Infant, Newborn
Infant, Premature
Necrotizing enterocolitis
Pediatric research
Randomized Controlled Trials as Topic
Review
Risk factors
title Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T17%3A47%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Current%20Research%20on%20the%20Epidemiology,%20Pathogenesis,%20and%20Management%20of%20Necrotizing%20Enterocolitis&rft.jtitle=Neonatology%20(Basel,%20Switzerland)&rft.au=Eaton,%20Simon&rft.date=2017-01-01&rft.volume=111&rft.issue=4&rft.spage=423&rft.epage=430&rft.pages=423-430&rft.issn=1661-7800&rft.eissn=1661-7819&rft_id=info:doi/10.1159/000458462&rft_dat=%3Cgale_pubme%3EA637318302%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1902482832&rft_id=info:pmid/28538238&rft_galeid=A637318302&rfr_iscdi=true