Impact of Muscarinic M 3 Receptor Antagonism on the Risk of Type 2 Diabetes in Antidepressant-Treated Patients: A Case-Controlled Study

M muscarinic receptor antagonism has been associated with glucose intolerance and disturbance of insulin secretion. Our objective was to examine the risk of type 2 diabetes mellitus (T2DM) in patients using antidepressants with and without M muscarinic receptor antagonism (AD_antaM and AD_nonantaM ,...

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Veröffentlicht in:	CNS drugs 2017-06, Vol.31 (6), p.483
Hauptverfasser:	Tran, Yen-Hao, Schuiling-Veninga, Catharina C M, Bergman, Jorieke E H, Groen, Henk, Wilffert, Bob
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Antidepressive Agents - administration & dosage Antidepressive Agents - adverse effects Antidepressive Agents - pharmacology Case-Control Studies Cohort Studies Databases, Factual Diabetes Mellitus, Type 2 - chemically induced Diabetes Mellitus, Type 2 - epidemiology Dose-Response Relationship, Drug Female Follow-Up Studies Humans Insulin - metabolism Insulin Secretion Male Middle Aged Receptor, Muscarinic M3 - agonists Risk Factors Sex Factors Time Factors
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