Effects of high-fat diet and fructose-rich diet on obesity, dyslipidemia and hyperglycemia in the WBN/Kob-Lepr fa rat, a new model of type 2 diabetes mellitus

Obesity and type 2 diabetes mellitus (T2DM) are occurring at epidemic-like rates, and these epidemics appear to have emerged largely from changes in daily diet. In the present study, we compared effects of high-fat diet (HFD) and fructose-rich diet (FRD) in WBN/Kob-Lepr (WBKDF) rats that spontaneous...

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Veröffentlicht in:	Journal of veterinary medical science 2017-06, Vol.79 (6), p.988
Hauptverfasser:	Namekawa, Junichi, Takagi, Yoshiichi, Wakabayashi, Kaoru, Nakamura, Yuki, Watanabe, Ayaka, Nagakubo, Dai, Shirai, Mitsuyuki, Asai, Fumitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Glucose - metabolism Diabetes Mellitus, Experimental - etiology Diabetes Mellitus, Type 2 - physiopathology Diet, High-Fat - adverse effects Disease Models, Animal Dyslipidemias - etiology Fructose - administration & dosage Hyperglycemia - etiology Male Obesity - etiology Rats Rats, Wistar
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