Pharmacokinetic and Pharmacodynamic Modeling of MOD-4023, a Long-Acting Human Growth Hormone, in Growth Hormone Deficiency Children

Background/Aims: MOD-4023 is a long-acting human growth hormone (hGH) in clinical trials for the treatment of growth hormone deficiency (GHD). A key goal is maintenance of serum concentrations of insulin-like growth factor (IGF) 1 within normal range throughout GH dosing. The study aimed to develop...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Hormone research in paediatrics 2017-01, Vol.87 (5), p.324-332
Hauptverfasser:	Fisher, Dennis M., Rosenfeld, Ron G., Jaron-Mendelson, Michal, Amitzi, Leanne, Koren, Ronit, Hart, Gili
Format:	Artikel
Sprache:	eng
Schlagworte:	Child Child, Preschool Female Human Growth Hormone - administration & dosage Human Growth Hormone - deficiency Human Growth Hormone - pharmacokinetics Humans Insulin-Like Growth Factor I - metabolism Male Models, Biological Original Paper
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!