Monoclonal Antibodies to Human Angiotensinogen: Development of an Elisa for Measurement of Hepatocyte Cultured Cells Content

We have prepared and purified a rabbit polyclonal antibody (PcAb) and two mouse monoclonal antibodies (McAbs) against human angiotensinogen. The PcAb (Kd: 4.0×10−12M) inhibits 50% of the hydrolytic activity of renin on angiotensinogen., at a final dilution of 1:800. The two monoclonal antibodies (Kd...

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Veröffentlicht in:	Clinical and experimental hypertension (1993) 1987, Vol.A9 (8-9), p.1479-1491
Hauptverfasser:	Mizrahi, J., Coezy, E., Auzan, C., Corvol, P., Menard, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensinogen - immunology Animals Antibodies, Monoclonal - immunology Carcinoma, Hepatocellular ELISA Enzyme-Linked Immunosorbent Assay Hepatocytes Human angiotensinogen Humans Liver - analysis Liver Neoplasms Mice Monoclonal antibodies Rabbits Radioimmunoassay Renin - antagonists & inhibitors Tumor Cells, Cultured
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