Calumenin contributes to ER-Ca 2+ homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention

Cystic Fibrosis (CF) is the most frequent fatal genetic disease in Caucasian populations. Mutations in the chloride channel CF Transmembrane Conductance Regulator (CFTR) gene are responsible for functional defects of the protein and multiple associated dysregulations. The most common mutation in pat...

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Veröffentlicht in:	Cell calcium (Edinburgh) 2017-03, Vol.62, p.47
Hauptverfasser:	Philippe, Réginald, Antigny, Fabrice, Buscaglia, Paul, Norez, Caroline, Huguet, Florentin, Castelbou, Cyril, Trouvé, Pascal, Becq, Frédéric, Frieden, Maud, Férec, Claude, Mignen, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	Bronchi - metabolism Bronchi - pathology Calcium - metabolism Calcium-Binding Proteins - metabolism Cells, Cultured Cystic Fibrosis Transmembrane Conductance Regulator - metabolism Endoplasmic Reticulum - metabolism Epithelial Cells - metabolism Homeostasis Humans
Online-Zugang:	Volltext
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