Enantioselective Effect of Flurbiprofen on Lithium Disposition in Rats

Aims: Lithium is administered for treating bipolar disorders and is mainly excreted into urine. Nonsteroidal anti-inflammatory drugs inhibit this process. In this study, we examined the enantioselective effect of flurbiprofen on the disposition of lithium in rats. Methods: Pharmacokinetic experiment...

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Veröffentlicht in:	Pharmacology 2017-01, Vol.99 (5-6), p.236-239
Hauptverfasser:	Uwai, Yuichi, Matsumoto, Masashi, Kawasaki, Tatsuya, Nabekura, Tomohiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Flurbiprofen - pharmacology Lithium Chloride - blood Lithium Chloride - pharmacokinetics Lithium Chloride - urine Male Rats Short Communications Stereoisomerism
Online-Zugang:	Volltext
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