A Population Pharmacokinetic Model for 51 Cr EDTA to Estimate Renal Function

Cr EDTA clearance (CL) from plasma is used to estimate glomerular filtration rate (GFR). We propose that current methods for analysing the raw Cr EDTA measurements over-simplifies the disposition of Cr EDTA and therefore could produce biased GFR estimates. The aim of this study was to develop a popu...

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Veröffentlicht in:	Clinical pharmacokinetics 2017-06, Vol.56 (6), p.671
Hauptverfasser:	Kuan, Isabelle H S, Duffull, Stephen B, Putt, Tracey L, Schollum, John B W, Walker, Robert J, Wright, Daniel F B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Chromium Radioisotopes Edetic Acid - blood Edetic Acid - pharmacokinetics Female Glomerular Filtration Rate Humans Kidney - physiology Kidney Diseases - blood Kidney Diseases - physiopathology Male Models, Biological Young Adult
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