Orientation of tyrosine side chain in neurotoxic Aβ differs in two different secondary structures of the peptide

Amyloid β (Aβ) peptide is present as a major component in amyloid plaque that is one of the hallmarks of Alzheimer's disease. The peptide contains a single tyrosine residue and Aβ has a major implication in the pathology of the disease progression. Current investigation revealed that the tyrosi...

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Veröffentlicht in:	Royal Society open science 2016-10, Vol.3 (10), p.160112-160112
Hauptverfasser:	Das, Swagata, Das, Supriya, Roy, Anupam, Pal, Uttam, Maiti, Nakul C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aβ Peptide Biochemistry And Biophysics Conformation Rotamer Tyrosine Fluorescence
Online-Zugang:	Volltext
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