Calpain mediated pulmonary vascular remodeling in hypoxia induced pulmonary hypertension

To explore the role of calpain in pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension and the underlying mechanisms.  Sprague-Dawley rats were randomly divided into the hypoxia group and the normoxia control group. Right ventricular systolic pressure (RVSP) and mean pulmonary art...

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Veröffentlicht in:	Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban 2016-09, Vol.41 (9), p.929
Hauptverfasser:	Zhang, Weifang, Zhu, Tiantian, Xiong, Aizhen, Ge, Xiaoyue, Xu, Ruilai, Lu, Shegui, Hu, Changping
Format:	Artikel
Sprache:	chi
Schlagworte:	Animals Calpain - genetics Calpain - physiology Cell Proliferation Dipeptides - physiology Hypertension, Pulmonary - chemically induced Hypertension, Pulmonary - genetics Hypertension, Pulmonary - physiopathology Hypertrophy, Right Ventricular Hypoxia Ki-67 Antigen - drug effects Myocytes, Smooth Muscle - physiology Proliferating Cell Nuclear Antigen - drug effects Pulmonary Artery Rats Rats, Sprague-Dawley Real-Time Polymerase Chain Reaction Up-Regulation Vascular Remodeling - genetics Vascular Remodeling - physiology
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