Mesenchymal stem cells attenuate ischemia–reperfusion injury after prolonged cold ischemia in a mouse model of lung transplantation: a preliminary study

Purpose Mesenchymal stem cells (MSCs) suppress inflammation and immune responses. We conducted this study to find out if MSCs attenuate ischemia–reperfusion injury in a mouse model of lung transplantation. Methods C57BL/6J mouse lungs perfused with low-potassium dextran glucose solution were preserv...

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Veröffentlicht in:	Surgery today (Tokyo, Japan) Japan), 2017-04, Vol.47 (4), p.425-431
Hauptverfasser:	Watanabe, Tatsuaki, Hoshikawa, Yasushi, Ishibashi, Naoya, Suzuki, Hirotoshi, Notsuda, Hirotsugu, Watanabe, Yui, Noda, Masafumi, Kanehira, Masahiko, Ohkouchi, Shinya, Kondo, Takashi, Okada, Yoshinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cold Temperature - adverse effects Ischemia - etiology Ischemia - therapy Lung - blood supply Lung Transplantation Male Medicine Medicine & Public Health Mesenchymal Stem Cell Transplantation - methods Mesenchymal Stromal Cells Mice, Inbred C57BL Models, Animal Original Article Pulmonary Artery Reperfusion Injury - etiology Reperfusion Injury - therapy Surgery Surgical Oncology Time Factors
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