Tumor evasion of humoral immunity mediated by proteolytic impairment of antibody triggered immune effector function

Immune suppression is recognized as a hallmark of cancer and this notion is largely based on studies on cellular immunity. Our recent studies have demonstrated a potential new mechanism of cancer suppression of immunity by impairment of antibody effector function mediated by proteolytic enzymes in t...

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Veröffentlicht in:	Oncoimmunology 2016-05, Vol.5 (5), p.e1122861-e1122861
Hauptverfasser:	Zhang, Ningyan, Jordan, Robert E., An, Zhiqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody immunity Author's View cancer immune evasion single proteolytic cleavage of the IgG hinge tumor microenvironment
Online-Zugang:	Volltext
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