Efficient access to sp 3 -rich tricyclic amine scaffolds through Diels-Alder reactions of azide-containing silyloxydienes

The preparation of sp -rich scaffolds to obtain more natural product-like libraries for incorporation into screening decks is challenging. Here, we describe the use of a Diels-Alder reaction between an enone and an azide-containing silyloxydiene to gain efficient access to complex tricyclic amine sc...

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Veröffentlicht in:	Tetrahedron 2016-06, Vol.72 (26), p.3766
Hauptverfasser:	McLeod, Michael C, Aubé, Jeffrey
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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