Precocious retinal adhesion is affected by furosemide and ouabain
A "precocious" adhesive force develops between the neurosensory retina (NSR) and the retinal pigment epithelium (RPE) 15-30 minutes after eyes are removed from day 15 embryonic chickens and incubated at 37°C. Precocious adhesion has been reported to be blocked by exposure to cold but to be...
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| Veröffentlicht in: | Current eye research 1989, Vol.8 (6), p.553-556 |
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| creator | Frambach, Donald A. Roy, Chandra E. Valentine, John L. Weiter, John J. |
| description | A "precocious" adhesive force develops between the neurosensory retina (NSR) and the retinal pigment epithelium (RPE) 15-30 minutes after eyes are removed from day 15 embryonic chickens and incubated at 37°C. Precocious adhesion has been reported to be blocked by exposure to cold but to be unaffected by exposure to furosemide and ouabain. Since RPE transport is thought to play a major role in the adhesion between the RPE and NSR of adult mammals, and since ouabain and furosemide block RPE transport in embryonic chickens, it has been thought that precocious adhesion in embryonic chickens is not a good model for studying adhesion between the RPE and the NSR of adult mammals. We have found, however, that when steps are taken to ensure that ouabain and furosemide reach the transport sites on RPE apical membrane before precocious adhesion develops, that ouabain and furosemide do affect precocious adhesion. |
| doi_str_mv | 10.3109/02713688908995753 |
| format | Article |
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Precocious adhesion has been reported to be blocked by exposure to cold but to be unaffected by exposure to furosemide and ouabain. Since RPE transport is thought to play a major role in the adhesion between the RPE and NSR of adult mammals, and since ouabain and furosemide block RPE transport in embryonic chickens, it has been thought that precocious adhesion in embryonic chickens is not a good model for studying adhesion between the RPE and the NSR of adult mammals. We have found, however, that when steps are taken to ensure that ouabain and furosemide reach the transport sites on RPE apical membrane before precocious adhesion develops, that ouabain and furosemide do affect precocious adhesion.</description><identifier>ISSN: 0271-3683</identifier><identifier>EISSN: 1460-2202</identifier><identifier>DOI: 10.3109/02713688908995753</identifier><identifier>PMID: 2743794</identifier><identifier>CODEN: CEYRDM</identifier><language>eng</language><publisher>Lisse: Informa UK Ltd</publisher><subject>Animals ; Anterior Eye Segment ; Biological and medical sciences ; Cell Adhesion - drug effects ; Chick Embryo ; Cold Temperature ; Dissection ; Eye and associated structures. Visual pathways and centers. Vision ; Fundamental and applied biological sciences. Psychology ; Furosemide - pharmacology ; Organ Culture Techniques ; Ouabain - pharmacology ; Pigment Epithelium of Eye - metabolism ; Retina - drug effects ; Retina - metabolism ; Temperature ; Vertebrates: nervous system and sense organs</subject><ispartof>Current eye research, 1989, Vol.8 (6), p.553-556</ispartof><rights>1989 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1989</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-a9a03c48a46d769e5f8084f60aa2dd5f73e1f6bac7f426bc83655823846df4783</citedby><cites>FETCH-LOGICAL-c430t-a9a03c48a46d769e5f8084f60aa2dd5f73e1f6bac7f426bc83655823846df4783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/02713688908995753$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/02713688908995753$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,780,784,4023,27922,27923,27924,59646,59752,60435,60541,61220,61255,61401,61436</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7277750$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2743794$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Frambach, Donald A.</creatorcontrib><creatorcontrib>Roy, Chandra E.</creatorcontrib><creatorcontrib>Valentine, John L.</creatorcontrib><creatorcontrib>Weiter, John J.</creatorcontrib><title>Precocious retinal adhesion is affected by furosemide and ouabain</title><title>Current eye research</title><addtitle>Curr Eye Res</addtitle><description>A "precocious" adhesive force develops between the neurosensory retina (NSR) and the retinal pigment epithelium (RPE) 15-30 minutes after eyes are removed from day 15 embryonic chickens and incubated at 37°C. Precocious adhesion has been reported to be blocked by exposure to cold but to be unaffected by exposure to furosemide and ouabain. Since RPE transport is thought to play a major role in the adhesion between the RPE and NSR of adult mammals, and since ouabain and furosemide block RPE transport in embryonic chickens, it has been thought that precocious adhesion in embryonic chickens is not a good model for studying adhesion between the RPE and the NSR of adult mammals. We have found, however, that when steps are taken to ensure that ouabain and furosemide reach the transport sites on RPE apical membrane before precocious adhesion develops, that ouabain and furosemide do affect precocious adhesion.</description><subject>Animals</subject><subject>Anterior Eye Segment</subject><subject>Biological and medical sciences</subject><subject>Cell Adhesion - drug effects</subject><subject>Chick Embryo</subject><subject>Cold Temperature</subject><subject>Dissection</subject><subject>Eye and associated structures. Visual pathways and centers. Vision</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Furosemide - pharmacology</subject><subject>Organ Culture Techniques</subject><subject>Ouabain - pharmacology</subject><subject>Pigment Epithelium of Eye - metabolism</subject><subject>Retina - drug effects</subject><subject>Retina - metabolism</subject><subject>Temperature</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0271-3683</issn><issn>1460-2202</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUFL5TAUhYMo-kb9AS6ELsRdNU3SJEU3Is4oCLrQdblNbniRttGkZXj_fvJ4bwQRXF245zuXkxNCTip6wSvaXFKmKi61bqhumlrVfIcsKiFpyRhlu2Sx1ssM8APyK6U3StcLsU_2mRJcNWJBbp4jmmB8mFMRcfIj9AXYJSYfxsKnApxDM6EtulXh5hgSDt5iAaMtwgwd-PGI7DnoEx5v5yF5_X33cntfPj79ebi9eSyN4HQqoQHKjdAgpFWywdppqoWTFIBZWzvFsXKyA6OcYLIzmsu61ozrzDuhND8k55u77zF8zJimdvDJYN_DiDl9qxqqqJQ8g9UGNDluiuja9-gHiKu2ou26tvZbbdlzuj0-dwPaT8e2p6yfbXVIBnoXYTQ-fWKKKaVqmrHrDeZHF-IAf0PsbTvBqg_xv4f_lOLqi32J0E9LAxHbtzDH_Dfphzf8A-TbmVo</recordid><startdate>1989</startdate><enddate>1989</enddate><creator>Frambach, Donald A.</creator><creator>Roy, Chandra E.</creator><creator>Valentine, John L.</creator><creator>Weiter, John J.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Swets & Zeitlinger</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1989</creationdate><title>Precocious retinal adhesion is affected by furosemide and ouabain</title><author>Frambach, Donald A. ; Roy, Chandra E. ; Valentine, John L. ; Weiter, John J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-a9a03c48a46d769e5f8084f60aa2dd5f73e1f6bac7f426bc83655823846df4783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Animals</topic><topic>Anterior Eye Segment</topic><topic>Biological and medical sciences</topic><topic>Cell Adhesion - drug effects</topic><topic>Chick Embryo</topic><topic>Cold Temperature</topic><topic>Dissection</topic><topic>Eye and associated structures. Visual pathways and centers. Vision</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Furosemide - pharmacology</topic><topic>Organ Culture Techniques</topic><topic>Ouabain - pharmacology</topic><topic>Pigment Epithelium of Eye - metabolism</topic><topic>Retina - drug effects</topic><topic>Retina - metabolism</topic><topic>Temperature</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Frambach, Donald A.</creatorcontrib><creatorcontrib>Roy, Chandra E.</creatorcontrib><creatorcontrib>Valentine, John L.</creatorcontrib><creatorcontrib>Weiter, John J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current eye research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Frambach, Donald A.</au><au>Roy, Chandra E.</au><au>Valentine, John L.</au><au>Weiter, John J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Precocious retinal adhesion is affected by furosemide and ouabain</atitle><jtitle>Current eye research</jtitle><addtitle>Curr Eye Res</addtitle><date>1989</date><risdate>1989</risdate><volume>8</volume><issue>6</issue><spage>553</spage><epage>556</epage><pages>553-556</pages><issn>0271-3683</issn><eissn>1460-2202</eissn><coden>CEYRDM</coden><abstract>A "precocious" adhesive force develops between the neurosensory retina (NSR) and the retinal pigment epithelium (RPE) 15-30 minutes after eyes are removed from day 15 embryonic chickens and incubated at 37°C. Precocious adhesion has been reported to be blocked by exposure to cold but to be unaffected by exposure to furosemide and ouabain. Since RPE transport is thought to play a major role in the adhesion between the RPE and NSR of adult mammals, and since ouabain and furosemide block RPE transport in embryonic chickens, it has been thought that precocious adhesion in embryonic chickens is not a good model for studying adhesion between the RPE and the NSR of adult mammals. We have found, however, that when steps are taken to ensure that ouabain and furosemide reach the transport sites on RPE apical membrane before precocious adhesion develops, that ouabain and furosemide do affect precocious adhesion.</abstract><cop>Lisse</cop><pub>Informa UK Ltd</pub><pmid>2743794</pmid><doi>10.3109/02713688908995753</doi><tpages>4</tpages></addata></record> |
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| ispartof | Current eye research, 1989, Vol.8 (6), p.553-556 |
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| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Animals Anterior Eye Segment Biological and medical sciences Cell Adhesion - drug effects Chick Embryo Cold Temperature Dissection Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Furosemide - pharmacology Organ Culture Techniques Ouabain - pharmacology Pigment Epithelium of Eye - metabolism Retina - drug effects Retina - metabolism Temperature Vertebrates: nervous system and sense organs |
| title | Precocious retinal adhesion is affected by furosemide and ouabain |
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