Antigenic variability: Obstacles on the road to vaccines against traditionally difficult targets

Despite the impressive impact of vaccines on public health, the success of vaccines targeting many important pathogens and cancers has to date been limited. The burden of infectious diseases today is mainly caused by antigenically variable pathogens (AVPs), which escape immune responses induced by p...

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Veröffentlicht in:	Human vaccines & immunotherapeutics 2016-10, Vol.12 (10), p.2640-2648
Hauptverfasser:	Servín-Blanco, R., Zamora-Alvarado, R., Gevorkian, G., Manoutcharian, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigenic Variation antigenically variable pathogens cancer vaccine combinatorial peptide library Communicable Diseases - immunology Genetic Variation HIV vaccine Humans Neoplasms - immunology Review Vaccines - immunology Vaccines - isolation & purification variable epitope library
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