Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect

We experimentally verify a speckle-based technique for noncontact measurement of glucose concentration in the bloodstream. The final device is intended to be a single wristwatch-style device containing a laser, a camera, and an alternating current (ac) electromagnet generated by a solenoid. The expe...

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Veröffentlicht in:Journal of biomedical optics 2016-06, Vol.21 (6), p.065001-065001
Hauptverfasser: Ozana, Nisan, Beiderman, Yevgeny, Anand, Arun, Javidi, Baharam, Polani, Sagi, Schwarz, Ariel, Shemer, Amir, Garcia, Javier, Zalevsky, Zeev
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container_end_page 065001
container_issue 6
container_start_page 065001
container_title Journal of biomedical optics
container_volume 21
creator Ozana, Nisan
Beiderman, Yevgeny
Anand, Arun
Javidi, Baharam
Polani, Sagi
Schwarz, Ariel
Shemer, Amir
Garcia, Javier
Zalevsky, Zeev
description We experimentally verify a speckle-based technique for noncontact measurement of glucose concentration in the bloodstream. The final device is intended to be a single wristwatch-style device containing a laser, a camera, and an alternating current (ac) electromagnet generated by a solenoid. The experiments presented are performed in vitro as proof of the concept. When a glucose substance is inserted into a solenoid generating an ac magnetic field, it exhibits Faraday rotation, which affects the temporal changes of the secondary speckle pattern distributions. The temporal frequency resulting from the ac magnetic field was found to have a lock-in amplification role, which increased the observability of the relatively small magneto-optic effect. Experimental results to support the proposed concept are presented.
doi_str_mv 10.1117/1.JBO.21.6.065001
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source MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Blood Chemical Analysis - instrumentation
Blood Chemical Analysis - methods
Blood Glucose - analysis
Humans
Lasers
Light
Magnets
Optics and Photonics
Rotation
title Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect
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