Biocompatibility and nanostructured materials: applications in nanomedicine
There has been huge interest in applications of nanomaterials in biomedical science, including diagnosis, drug delivery, and development of human organs. Number of these nanomaterials has been already studied in human or at pre-clinical trial. There is a growing concern on potential toxicity and adv...
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Veröffentlicht in: | Artificial cells, nanomedicine, and biotechnology nanomedicine, and biotechnology, 2017-06, Vol.45 (4), p.833-842 |
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creator | Adabi, Mahdi Naghibzadeh, Majid Adabi, Mohsen Zarrinfard, Mohammad Ali Esnaashari, Seyedeh Sara Seifalian, Alexander M. Faridi-Majidi, Reza Tanimowo Aiyelabegan, Hammed Ghanbari, Hossein |
description | There has been huge interest in applications of nanomaterials in biomedical science, including diagnosis, drug delivery, and development of human organs. Number of these nanomaterials has been already studied in human or at pre-clinical trial. There is a growing concern on potential toxicity and adverse effects of nanomaterials on human health, including lack of standard method of assessment of toxicology of these materials. Our investigation indicated that the bare and small nanoparticle have higher toxicity than modified and bulk materials, respectively. In addition, spherical nanoparticles have less toxicity than rod nanoparticles due to immune response of body. |
doi_str_mv | 10.1080/21691401.2016.1178134 |
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In addition, spherical nanoparticles have less toxicity than rod nanoparticles due to immune response of body.</description><subject>Animals</subject><subject>Biocompatibility</subject><subject>Biocompatible Materials - chemistry</subject><subject>Biocompatible Materials - metabolism</subject><subject>Biocompatible Materials - toxicity</subject><subject>Biomedical materials</subject><subject>blood brain barrier</subject><subject>Drug delivery</subject><subject>Drug delivery systems</subject><subject>Humans</subject><subject>Immune response</subject><subject>Immune system</subject><subject>Nanomaterials</subject><subject>Nanomedicine - methods</subject><subject>Nanoparticles</subject><subject>Nanostructured materials</subject><subject>Nanostructures - chemistry</subject><subject>Nanostructures - toxicity</subject><subject>Nanotechnology</subject><subject>Organs</subject><subject>polymer</subject><subject>Toxicity</subject><subject>Toxicology</subject><issn>2169-1401</issn><issn>2169-141X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLxDAQgIMo7rLuT1AKXrzsmmnTJPWkLr5wwYuCt5C2CWRpk5q0yP57s-7j4MG5zDB88-BD6BzwHDDH1ynQAgiGeYqBzgEYh4wcofGmPwMCn8eHGsMITUNY4RgcKMvJKRqlLCUMCjJGr_fGVa7tZG9K05h-nUhbJ1ZaF3o_VP3gVZ20slfeyCbcJLLrGlNF2tmQGPtLtqo2lbHqDJ3oCKnpLk_Qx-PD--J5tnx7elncLWcVYaSf6ZTQLD6mclbUUnPFcSZTnde6qBnNc5IqkhNeAAUuqWalLLOy0EpxXWqudTZBV9u9nXdfgwq9aE2oVNNIq9wQBBQYWEY5pBG9_IOu3OBt_E4A51ECxXhD5Vuq8i4Er7TovGmlXwvAYiNc7IWLjXCxEx7nLnbbhzJKOEzt9UbgdgsYq51v5bfzTS16uW6c117aygSR_X_jB6p8j3A</recordid><startdate>20170601</startdate><enddate>20170601</enddate><creator>Adabi, Mahdi</creator><creator>Naghibzadeh, Majid</creator><creator>Adabi, Mohsen</creator><creator>Zarrinfard, Mohammad Ali</creator><creator>Esnaashari, Seyedeh Sara</creator><creator>Seifalian, Alexander M.</creator><creator>Faridi-Majidi, Reza</creator><creator>Tanimowo Aiyelabegan, Hammed</creator><creator>Ghanbari, Hossein</creator><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20170601</creationdate><title>Biocompatibility and nanostructured materials: applications in nanomedicine</title><author>Adabi, Mahdi ; Naghibzadeh, Majid ; Adabi, Mohsen ; Zarrinfard, Mohammad Ali ; Esnaashari, Seyedeh Sara ; Seifalian, Alexander M. ; Faridi-Majidi, Reza ; Tanimowo Aiyelabegan, Hammed ; Ghanbari, Hossein</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-f2463140e579daf8e803a2f5df9d765542e454891618a6f7bab3b9fee8fbf8ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Biocompatibility</topic><topic>Biocompatible Materials - chemistry</topic><topic>Biocompatible Materials - metabolism</topic><topic>Biocompatible Materials - toxicity</topic><topic>Biomedical materials</topic><topic>blood brain barrier</topic><topic>Drug delivery</topic><topic>Drug delivery systems</topic><topic>Humans</topic><topic>Immune response</topic><topic>Immune system</topic><topic>Nanomaterials</topic><topic>Nanomedicine - methods</topic><topic>Nanoparticles</topic><topic>Nanostructured materials</topic><topic>Nanostructures - chemistry</topic><topic>Nanostructures - toxicity</topic><topic>Nanotechnology</topic><topic>Organs</topic><topic>polymer</topic><topic>Toxicity</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Adabi, Mahdi</creatorcontrib><creatorcontrib>Naghibzadeh, Majid</creatorcontrib><creatorcontrib>Adabi, Mohsen</creatorcontrib><creatorcontrib>Zarrinfard, Mohammad Ali</creatorcontrib><creatorcontrib>Esnaashari, Seyedeh Sara</creatorcontrib><creatorcontrib>Seifalian, Alexander M.</creatorcontrib><creatorcontrib>Faridi-Majidi, Reza</creatorcontrib><creatorcontrib>Tanimowo Aiyelabegan, Hammed</creatorcontrib><creatorcontrib>Ghanbari, Hossein</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Artificial cells, nanomedicine, and biotechnology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Adabi, Mahdi</au><au>Naghibzadeh, Majid</au><au>Adabi, Mohsen</au><au>Zarrinfard, Mohammad Ali</au><au>Esnaashari, Seyedeh Sara</au><au>Seifalian, Alexander M.</au><au>Faridi-Majidi, Reza</au><au>Tanimowo Aiyelabegan, Hammed</au><au>Ghanbari, Hossein</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biocompatibility and nanostructured materials: applications in nanomedicine</atitle><jtitle>Artificial cells, nanomedicine, and biotechnology</jtitle><addtitle>Artif Cells Nanomed Biotechnol</addtitle><date>2017-06-01</date><risdate>2017</risdate><volume>45</volume><issue>4</issue><spage>833</spage><epage>842</epage><pages>833-842</pages><issn>2169-1401</issn><eissn>2169-141X</eissn><abstract>There has been huge interest in applications of nanomaterials in biomedical science, including diagnosis, drug delivery, and development of human organs. 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subjects | Animals Biocompatibility Biocompatible Materials - chemistry Biocompatible Materials - metabolism Biocompatible Materials - toxicity Biomedical materials blood brain barrier Drug delivery Drug delivery systems Humans Immune response Immune system Nanomaterials Nanomedicine - methods Nanoparticles Nanostructured materials Nanostructures - chemistry Nanostructures - toxicity Nanotechnology Organs polymer Toxicity Toxicology |
title | Biocompatibility and nanostructured materials: applications in nanomedicine |
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