Biologically optimized helium ion plans: calculation approach and its in vitro validation

Treatment planning studies on the biological effect of raster-scanned helium ion beams should be performed, together with their experimental verification, before their clinical application at the Heidelberg Ion Beam Therapy Center (HIT). For this purpose, we introduce a novel calculation approach ba...

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Veröffentlicht in:	Physics in medicine & biology 2016-06, Vol.61 (11), p.4283-4299
Hauptverfasser:	Mairani, A, Dokic, I, Magro, G, Tessonnier, T, Kamp, F, Carlson, D J, Ciocca, M, Cerutti, F, Sala, P R, Ferrari, A, Böhlen, T T, Jäkel, O, Parodi, K, Debus, J, Abdollahi, A, Haberer, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Cell Line, Tumor Cell Survival - radiation effects experimental validation hadron therapy Helium - therapeutic use helium ions Humans Radioisotopes - therapeutic use Radiotherapy Planning, Computer-Assisted - methods RBE calculations Relative Biological Effectiveness
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